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Today's Date: May 2, 2024

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Study: Kidney Disease A Big Risk For Younger, Low-Income Minorities

Washington, DC — Chronic kidney disease (CKD) afflicts a large

number of younger minority adults receiving medical care in settings that serve the

uninsured and underinsured (settings collectively known as the healthcare safety net).

Poor, minority adults with moderate to severe CKD are also two to four times more likely

to progress to kidney failure than non-Hispanic whites. These are the findings from a

study published online in the Clinical Journal of the American Society of Nephrology

(CJASN).

The study indicates that targeted efforts to assess the burden and progression of CKD

within the healthcare safety net are vital to improving the quality of care for this

vulnerable population, and ultimately save lives.

Researchers at the University of Washington, the University of California San Francisco,

and Stanford University examined data from 15,353 adults with non-dialysis dependent

CKD stages 3-5. All were receiving regular ambulatory care in the Community Health

Network of San Francisco and were followed for a period of 12-months to 9.4 years. The

study authors measured the time it took for patients to progress from moderate to

severe CKD to end-stage renal disease (ESRD) or death.

The vast majority of study participants were indigent, 40 percent were either uninsured

or enrolled in Medicaid, and one-third spoke a primary language other than English – all

vulnerable populations which have been underrepresented in prior studies of CKD.

In contrast to the general population and prior CKD studies in the United States, the

study authors found CKD afflicted a large fraction of young adults (20-39 years old),

most of whom were racial or ethnic minorities. Overall, African Americans, Hispanics,

Asians and Pacific Islanders with CKD were at higher risk of developing ESRD,

compared with non-Hispanic whites.

“Minorities in the United States are two to four times more likely than non-minorities to

progress to ESRD,” said Andy I. Choi, M.D., M.A.S., study co-author and assistant

professor, Division of Nephrology, University of California, San Francisco. “That

represents a significant disparity that warrants greater study about the causes,

consequences and preventive measures appropriate for people in this demographic.”

Because so little is known about CKD in the healthcare safety net, the authors call for

additional research to assess what is needed to curb the progression of the disease,

particularly among vulnerable populations. “More targeted research in these public

healthcare and safety net settings is necessary to identify ways to slow the progression

of the disease among the urban poor with CKD, thereby reducing disability and

improving overall survival," said Yoshio N. Hall, M.D., study co-author and assistant

professor of medicine, Kidney Research Institute, Division of Nephrology, University of

Washington.

“Kidney disease is a growing problem in the United States, doubling in incidence over

the last two decades. It’s serious, and without proper diagnosis and treatment, kidney

disease can lead to expensive treatments like transplantation or dialysis,” said Sharon

Anderson, M.D., FASN, president of the American Society of Nephrology. “Health care

providers need to be especially vigilant screening patients who are most at-risk for

developing kidney disease – minorities, seniors and those who have been diagnosed

with diabetes, hypertension and/or cardiovascular disease."

The study was published in conjunction with World Kidney Day, an international

effort to raise awareness about the growing incidence of kidney disease and the need

for increased funding for kidney disease research and education. Experts say more

research can lead to treatments that could prevent or slow the disease’s progression,

save lives and reduce treatment costs. Currently, more than 26 million Americans, or one

in nine adults, have chronic kidney disease. For more information about kidney disease

and World Kidney Day, visit www.asn-online.org.

The article, entitled “Chronic Kidney Disease in the Urban Poor,” appears online at

http://cjasn.asnjournals.org/ doi 10.2215/CJN.09011209. ASN has released an

accompanying podcast with Dr. Hall, which is available on iTunes and on the

ASN website at www.asn-online.org.

The content of this article does not reflect the views or opinions of The American Society

of Nephrology (ASN). Responsibility for the information and views expressed therein lies

entirely with the author(s). ASN does not offer medical advice. All content in ASN

publications is for informational purposes only, and is not intended to cover all possible

uses, directions, precautions, drug interactions, or adverse effects. This content should

not be used during a medical emergency or for the diagnosis or treatment of any medical

condition. Please consult your doctor or other qualified health care provider if you have

any questions about a medical condition, or before taking any drug, changing your diet

or commencing or discontinuing any course of treatment. Do not ignore or delay

obtaining professional medical advice because of information accessed through ASN.

Call 911 or your doctor for all medical emergencies.

Founded in 1966, the American Society of Nephrology (ASN) is the world’s largest

professional society devoted to the study of kidney disease. Comprised of 11,000

physicians and scientists, ASN continues to promote expert patient care, to advance

medical research, and to educate the renal community. ASN also informs policymakers

about issues of importance to kidney doctors and their patients. ASN funds research,

and through its world-renowned meetings and first-class publications, disseminates

information and educational tools that empower physicians.

# # #

ASN Contact: Amy Martin • 202-745-5118 (p) • amartin@gymr.com

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